Robert W Sauerwein Selected Research

Chloroquine (Aralen)

1/2019	Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis.
3/2016	Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial.
3/2015	Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria.
2/2015	Blood-stage immunity to Plasmodium chabaudi malaria following chemoprophylaxis and sporozoite immunization.
1/2015	Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites.
11/2014	Cytotoxic markers associate with protection against malaria in human volunteers immunized with Plasmodium falciparum sporozoites.
9/2014	Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity.
4/2014	Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum.
1/2014	Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report.
1/2014	Sporozoite immunization of human volunteers under mefloquine prophylaxis is safe, immunogenic and protective: a double-blind randomized controlled clinical trial.

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Robert W Sauerwein Research Topics

Disease

132	Malaria 03/2022 - 10/2002
76	Infections 03/2022 - 03/2004
18	Bites and Stings (Sting) 03/2022 - 01/2011
15	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2021 - 08/2004
12	Parasitemia 01/2022 - 08/2004
4	Inflammation (Inflammations) 03/2022 - 01/2009
3	Communicable Diseases (Infectious Diseases) 01/2018 - 01/2013
3	Anemia 05/2010 - 01/2009
3	Human Influenza (Influenza) 09/2008 - 05/2007
2	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2021
2	Neoplasms (Cancer) 01/2021 - 02/2015
2	Hemolysis 09/2015 - 05/2010
1	Convalescence 01/2022
1	Bacteremia 01/2021
1	Tuberculosis (Tuberculoses) 01/2019
1	Parasitic Diseases (Parasitic Disease) 01/2017
1	Asymptomatic Infections 10/2016
1	Breakthrough Infections 12/2015
1	Vivax Malaria 09/2015

Drug/Important Bio-Agent (IBA)

47	VaccinesIBA 01/2022 - 08/2004
24	1- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA 03/2022 - 08/2012
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2007
20	Pharmaceutical PreparationsIBA 01/2022 - 12/2006
19	AntigensIBA 01/2022 - 08/2006
18	Chloroquine (Aralen)FDA LinkGeneric 01/2019 - 03/2005
15	Malaria VaccinesIBA 01/2020 - 08/2004
14	AntibodiesIBA 01/2022 - 03/2006
13	Antimalarials (Antimalarial Agents)IBA 01/2022 - 09/2005
10	artemisinin (artemisinine)IBA 09/2015 - 04/2006
9	CytokinesIBA 03/2022 - 07/2007
5	Biological ProductsIBA 01/2020 - 01/2009
4	Monoclonal AntibodiesIBA 12/2021 - 01/2015
4	EpitopesIBA 10/2020 - 02/2012
4	Complement System Proteins (Complement)IBA 01/2018 - 07/2007
3	Interleukin-6 (Interleukin 6)IBA 03/2022 - 06/2009
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2009
3	pyrimethamine drug combination fanasil (Fansidar)FDA Link 09/2015 - 06/2005
3	Nucleic AcidsIBA 01/2014 - 03/2007
3	VirosomesIBA 09/2008 - 05/2007
3	Subunit VaccinesIBA 01/2008 - 05/2007
2	von Willebrand FactorIBA 01/2022 - 08/2007
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021 - 09/2017
2	Luminescent ProteinsIBA 01/2020 - 01/2019
2	EnzymesIBA 01/2019 - 08/2009
2	Immunoglobulin G (IgG)IBA 01/2017 - 04/2014
2	artenimol (dihydroartemisinin)IBA 09/2014 - 06/2013
2	Mefloquine (Lariam)FDA LinkGeneric 09/2014 - 01/2014
2	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 06/2013 - 12/2006
2	InterferonsIBA 03/2011 - 12/2010
2	Surface Antigens (Surface Antigen)IBA 01/2011 - 08/2006
2	ArtesunateIBA 05/2010 - 06/2005
2	HepcidinsIBA 06/2009 - 01/2009
2	IronIBA 06/2009 - 01/2009
2	ProteomeIBA 10/2008 - 10/2002
2	TetraspaninsIBA 09/2008 - 05/2006
2	CholesterolIBA 09/2008 - 05/2006
2	Peptides (Polypeptides)IBA 12/2007 - 05/2007
2	Protein Subunit VaccinesIBA 12/2007 - 05/2007
2	DNA (Deoxyribonucleic Acid)IBA 07/2007 - 11/2006
1	Interleukin-8 (Interleukin 8)IBA 03/2022
1	P-SelectinIBA 01/2022
1	Thrombin FDA Link 01/2022
1	Recombinant ProteinsIBA 01/2021
1	PhloretinIBA 01/2021
1	Fluconazole (Zonal)FDA LinkGeneric 01/2021
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2021
1	AC133 AntigenIBA 01/2021
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2020
1	Saline SolutionIBA 01/2020
1	Natural Cytotoxicity Triggering Receptor 3IBA 01/2019
1	BCG Vaccine FDA Link 01/2019
1	pantothenamideIBA 01/2019
1	p 230 (p230)IBA 10/2018
1	AldehydesIBA 01/2018
1	Macrophage Colony-Stimulating FactorIBA 01/2018
1	Glutamic Acid (Glutamate)FDA Link 09/2017
1	alpha-aminopyridineIBA 01/2017
1	MMV390048IBA 01/2017
1	ACT-451840IBA 10/2016
1	RNA (Ribonucleic Acid)IBA 10/2016
1	InsecticidesIBA 04/2016
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 03/2016
1	multidrug resistance-associated protein 1IBA 03/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 02/2016
1	IonophoresIBA 09/2015
1	Histocompatibility Antigens Class IIIBA 09/2015
1	GlycolipidsIBA 09/2015
1	Coenzyme A (CoA)IBA 04/2015
1	Ivermectin (Mectizan)FDA Link 02/2015
1	DDD107498IBA 01/2015
1	Peptide Elongation Factor 2 (EF-2)IBA 01/2015
1	Guanosine Triphosphate (GTP)IBA 01/2015

Therapy/Procedure

11	Chemoprevention 01/2020 - 01/2012
7	Therapeutics 01/2019 - 04/2006
6	Aftercare (After-Treatment) 01/2021 - 04/2006
5	Mass Drug Administration 01/2018 - 05/2010
3	Intradermal Injections 05/2015 - 01/2013
1	Intravenous Administration 03/2022
1	Injections 12/2015